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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP5
All Species:
32.73
Human Site:
T137
Identified Species:
51.43
UniProt:
Q8N3R9
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3R9
NP_071919.2
675
77294
T137
S
L
K
H
I
Q
H
T
L
V
D
S
Q
S
Q
Chimpanzee
Pan troglodytes
XP_510014
764
85553
T226
S
L
K
H
I
Q
H
T
L
V
D
S
Q
S
Q
Rhesus Macaque
Macaca mulatta
XP_001105724
674
77301
T137
S
L
K
H
I
Q
H
T
L
V
D
S
Q
S
Q
Dog
Lupus familis
XP_547862
675
77214
T137
S
L
K
H
I
Q
H
T
L
V
D
S
Q
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLB2
675
77211
T137
S
L
K
H
I
Q
H
T
L
V
D
S
Q
S
Q
Rat
Rattus norvegicus
Q5U2Y3
576
65604
K117
V
H
D
T
V
A
Q
K
S
Y
D
P
V
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505475
675
76860
T137
S
L
K
H
I
Q
H
T
L
V
D
S
Q
S
Q
Chicken
Gallus gallus
Q5ZJ00
468
52501
S13
G
R
G
G
G
G
G
S
G
S
M
R
T
A
L
Frog
Xenopus laevis
NP_001085267
675
76810
T137
S
L
K
D
I
Q
H
T
L
V
D
S
Q
S
Q
Zebra Danio
Brachydanio rerio
Q8JHF4
677
76390
S138
S
L
K
Q
V
Q
H
S
L
N
D
S
Q
S
Q
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
L12
S
N
K
N
E
P
A
L
I
L
D
S
V
T
S
Fruit Fly
Dros. melanogaster
Q24210
898
100893
T331
T
D
A
D
M
P
I
T
G
A
T
D
E
W
A
Honey Bee
Apis mellifera
XP_393395
1033
115664
L469
E
L
E
A
V
R
T
L
L
V
Q
S
R
F
A
Nematode Worm
Caenorhab. elegans
P54936
961
108794
G169
P
L
K
L
C
G
F
G
V
A
K
D
L
S
E
Sea Urchin
Strong. purpuratus
XP_784409
971
107892
K434
T
L
S
L
A
Q
N
K
L
G
S
P
Q
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.6
97
98.2
N.A.
96.7
36.2
N.A.
93.7
25
86
77
25.7
26.7
34.7
24.1
34.7
Protein Similarity:
100
87.5
97.7
99.5
N.A.
98.6
54.9
N.A.
96.8
43.8
92.5
86.7
44.5
46.3
49.2
41.7
49.2
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
100
0
93.3
73.3
26.6
6.6
26.6
20
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
13.3
93.3
86.6
53.3
26.6
53.3
33.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
7
7
7
0
0
14
0
0
0
7
14
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
14
0
0
0
0
0
0
67
14
0
7
0
% D
% Glu:
7
0
7
0
7
0
0
0
0
0
0
0
7
0
7
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
0
% F
% Gly:
7
0
7
7
7
14
7
7
14
7
0
0
0
0
0
% G
% His:
0
7
0
40
0
0
54
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
47
0
7
0
7
0
0
0
0
0
0
% I
% Lys:
0
0
67
0
0
0
0
14
0
0
7
0
0
0
0
% K
% Leu:
0
74
0
14
0
0
0
14
67
7
0
0
7
7
7
% L
% Met:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
7
0
7
0
0
7
0
0
7
0
0
0
0
0
% N
% Pro:
7
0
0
0
0
14
0
0
0
0
0
14
0
0
7
% P
% Gln:
0
0
0
7
0
60
7
0
0
0
7
0
60
0
54
% Q
% Arg:
0
7
0
0
0
7
0
0
0
0
0
7
7
0
7
% R
% Ser:
60
0
7
0
0
0
0
14
7
7
7
67
0
60
7
% S
% Thr:
14
0
0
7
0
0
7
54
0
0
7
0
7
7
0
% T
% Val:
7
0
0
0
20
0
0
0
7
54
0
0
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _